One of the largest studies to date to examine the relationship between single or multiple intravitreal injections of Avastin (bevacizumab) for wet macular degeneration, studying several thousand patients from British Columbia in Canada, has not found any increased risk of myocardial infarction (heart attack) or stroke in patients receiving the injections:
http://www.ajo.com/article/S0002-9394%2815%2930005-2/abstract
This is obviously reassuring news for the many patients receiving Avastin injections for their eye condition!